Nicholas E. Navin, Ph.D.

Associate Professor
Dept. of Genetics Dept. of Bioinformatics Director,
CPRIT Single Cell Genomics Center Co-Director,
Sequencing Core MD Anderson Cancer Center

Dr. Nicholas Navin is a tenured associate professor in the Department of Genetics and the Department of Bioinformatics and Computational Biology at the MD Anderson Cancer Center. He is also the director of the CPRIT Single Cell Genomics Center and the co-director of the Sequencing and Microarray Core Facility. Dr. Navin completed his Ph.D. and postdoctoral studies at the Cold Spring Harbor Laboratory and Stony Brook University.

Dr. Navin is internationally recognized for his seminal work on developing single cell DNA sequencing techniques to study cancer. Dr. Navin developed the first single cell DNA sequencing method (Navin et al. 2011 Nature, citations: 1851) which played a pivotal role in establishing the field of single cell genomics. His research work focuses on understanding clonal evolution in cancer, in the context of invasion, metastasis and therapy resistance. His previous studies have identified a punctuated model of copy number evolution in breast cancer, multi-clonal invasion in DCIS breast cancer and transcriptional reprogramming during chemotherapy resistance in triple-negative disease. The Navin lab is collaborating closely with clinical groups at MD Anderson to translate single cell sequencing technologies into the clinic, where they are poised to have a big impact on improving diagnostic modalities and treatment strategies in human patients. Dr. Navin has been the recipient of many awards, including the AAAS Wachtel Award, 40 under 40 award, ACS Research Scholar Award, Andrew Sabin Fellowship, Wilson Stone Award, Randall Innovator Award, Living Legend Basic Science Award and Damon-Runyon Innovator Award.